Police responded to the call at Unique Treasures on Highway 65 South to find the store owner had been shot in the face and arm. He was still able to describe what happened.
Phillip Engles, 27, was identified as being the shooter and is believed to be acting alone.
He was disarmed by the victim and fled the scene with more than $1,000 in stolen merchandise.
After dropping off the vehicle used in the robbery as well as some of the stolen items at a home in southern Boone County, Engles and a female companion fled to a remote area on the Boone County and Newton County line, according to the Boone County Sheriff's Office (BCSO).
Engles left Mandy Engles, 29, during his flight from the approaching officers, the BCSO said.
She was taken into custody and is awaiting formal charges.
Tracking dogs were used, but they were unable to locate the suspect.
The BCSO says when Engles is captured he will face charges of attempted capital murder, aggravated robbery and theft.
Deputies say Engles should be considered armed and dangerous.
The store owner who was shot int he robbery was in good condition at a Springfield, Missouri hospital at last report.