According to Arkansas State Police, 18-year-old Tavoceya L. Harris was driving north on Highway 15 just south of England when he lost control of the vehicle and ran off the road.
The 2005 Chrysler Pacifica then hit a ditch and flipped.
The passenger, 3-year-old Paisley J. Palmer-Blanchard, was ejected from the vehicle.
She was pronounced dead at the scene and taken to Roller England Funeral Home.
Harris was taken to Baptist Medical Center in North Little Rock with unknown injuries.
Neither the driver nor the passenger were wearing a seat belt.