According to the Jonesboro Police Department, three people were arrested after DEA agents, Craighead County Sheriff's officers, and Jonesboro SWAT team members executed the search warrant and found the drugs.
The 10 pounds of methamphetamine ice has a street value of approximately $85 per gram, according to police.
That brings the approximate total value of the drugs to $385,050.
Police say the investigation is ongoing, and is not related to the 30 people who were indicted on Wednesday in another federal drug bust.
The names of the three people arrested have not been released.