Conner Cox, 14, cut off more than 12 inches of hair for the Locks of Love donation on Tuesday.
He told KARK he was inspired to take on the project in memory of his grandmother.
"My Mimi, my mom's mother, she had red hair, but she died of cancer. I never got to meet her, but I've seen pictures of her," Cox said. "So, I've been growing my hair for the past five years."
Cox feels good about the decision to donate his hair, thinking of kids who suffer from the same disease that's taken members of his family.
"It makes me feel really good cause a lot of people don't realize what people are having to go through," Cox said. "I'm making a point to a lot of people that it's good to spend your time growing out your hair for someone else who doesn't have it."
Cox left some length to his head of hair even after chopping off the full foot. He plans to continue growing his hair for the Locks of Love Program.
Each hairpiece requires about six of the ponytails of hair like Cox donated on Tuesday. To find out how to get involved or what the program's all about, click here.