The Arkansas native and "Rhinestone Cowboy" is planning a concert at the Robinson Center on September 6.
Tickets go on sale Friday, July 20 and begin at $50.
The 75-year-old Delight (Pike County) native is known for hits like 1967's "Gentle on My Mind," and "By the Time I Get to Phoenix", as well as the 1975 single of the year "Rhinestone Cowboy."
Campbell disclosed his Alzheimer's diagnosis in June of 2011 prior to announcing his farewell tour.
Campbell, who has won eight Grammy Awards, learned of his diagnosis roughly six months prior to his public announcement.