Catholic officials expect more than one-million people to attend the ceremony in St. Peter's Square that moves the late pontiff a step closer to becoming a saint.
In order to be beatified, the person must be declared by the Catholic Church to have facilitated a miracle.
As part of the beatification ceremony, a prayer vigil will be held in Rome.
The day after, a mass of thanksgiving will be conducted and John Paul's remains will be placed in a new location in a side chapel of St Peter's Basilica.
His coffin currently lies in the crypts below.