The Saline County Sheriff's Office (SCSO) says Joseph Gonsalves, 48, died in the Saturday night attack that happened inside his home on North Detonti Road shortly after eight o'clock.
He was pronounced dead after being taken to the hospital by ambulance, deputies say.
The SCSO says the stabbing followed a disturbance that also involved Gonsalves' wife.
Jonathan Albertsen, 23, was arrested at the scene. He is charged with first degree murder and is being held without bond.